Figure 5.
Acetylation profile of histone H3 in the hGATA1 locus. The organization of the figure is the same as in Figure 4. Top, the hGATA1 locus is drawn. Genes are depicted as black boxes. Below the locus, positions of hematopoietic (gray arrows), eosinophil-specific (open arrows), and widely expressed DNase I HSs (black arrows) are marked. Below that, the panels show the profile of acetylated H3 at different points along the hGATA1 locus in primary erythroid cells (Io erythroid), primary eosinophils (Io eosinophils), fibroblast cell line (HeLa), and Io neutrophils. Data are shown as average fold enrichments from duplicate real-time PCR reactions performed on 3 independent ChiP preparations. Error bars (1 SD) are shown.