Refinement of the cdr on chromosome 2 and identification of candidate tumor suppressor genes within the cdr. (A) Genotype of tumors (listed on left) with polymorphic D2Mit and WC200/1 markers. C indicates CBAallele retained; S, SJL allele retained; H and gray shading, heterozygous. (B) The cdr, which represents the minimal region where all the tumors with deletions exhibit LOH. The positions of 13 genes that we have mapped,²²  including 3 candidate tumor suppressors (bold), are indicated. Their positions largely agree with those in the provisional database sequence for chromosome 2, but the 3 genes in the lower row are ambiguously mapped with respect to those immediately above them in the upper row.