Lack of correlation between AID protein levels and ASHM in DLBCL. (Top) AID protein expression levels in DLBCL samples displaying (•) or lacking (○) ASHM, as defined by the presence of mutations in PIM1, PAX5, cMYC, and RhoH/TTF. AID protein levels were measured by Western blot analysis and normalized for β-actin as described in “Materials and methods.” (Bottom) Histograms show the average expression levels in the 2 groups. Error bars indicate standard deviations.