Ischemia-induced mobilization of BM progenitor cells in PB and modulation of plasma and BM levels of SDF-1 following ischemia. (A) C-kit⁺ cells were evaluated by analyzing 10⁴ peripheral blood mononuclear cells at the indicated time points. *P < .05; #P = .05; n = 6, for each experimental group. (B) ELISA tests revealed a rise in the SDF-1 plasma levels shortly after induction of ischemia. *P < .05; n = 4, for each experimental group. (C) Decrease of SDF-1 BM concentration of SDF-1 as evaluated by ELISA test of bone marrow obtained from the ischemic limbs.¹⁰  *P < .05; n = 3, for each experimental group. Error bars indicate standard errors.