Figure 5.
Supervised analysis of CD45RAhiCD7+, CD45RAintCD7-, and CD45RAhiLin-CD10+ HPC gene expression profiles. Genes discriminating between the 3 cell populations were selected by using the classification analysis module of Array Miner 4.1 (see “Materials and methods”) and were plotted according to average signal intensity (ASI). Relative expression levels of genes differentially expressed in (A) CD45RAhiCD7+, (B) CD45RAintCD7-, and (C) CD45RAhiLin-CD10+ HPCs. Among the 381 probe sets differentially expressed in CD45RAhiLin-CD10+ HPCs, only those corresponding to genes underlying polarization toward the B lineage are presented.