In vivo detection of telomerase activity of 3 TERC mutations with their corresponding complementary mutations and the double TERC mutations, in which the secondary structure is repaired. The arrows denote the start of the TRAP ladder (TRAP), the corresponding internal control (IC), and the control of the assay where an equal amount of RNA was loaded (RNA) or the levels of luciferase was measured (Luc) to control for the corresponding TRAP experiment.