Figure 5.
Figure 5. Stimulation of PAI-1 synthesis with thrombin. To investigate whether the platelets could be stimulated to increase the synthesis rate, platelets were incubated for 1, 3, and 6 hours, as described in Figure 3, in the absence or presence of 0.1 U/mL thrombin. Thrombin activation was found to increase the rate of PAI-1 synthesis.

Stimulation of PAI-1 synthesis with thrombin. To investigate whether the platelets could be stimulated to increase the synthesis rate, platelets were incubated for 1, 3, and 6 hours, as described in Figure 3, in the absence or presence of 0.1 U/mL thrombin. Thrombin activation was found to increase the rate of PAI-1 synthesis.

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