Figure 1.
Retinoid-dependent expression of CHOP mRNA in acute leukemia cell lines. U937 and U937PR9 (U937 stably transfected with zinc-inducible PML/RARα) cells were incubated with or without ZnSO4 (100 μM, 16 hours), with or without ATRA (10-8 M, 4 hours), and were analyzed for CHOP expression by Northern blot. Blots were stripped and rehybridized with GAPDH.