Figure 5.
Septic plasma and soluble MD-2 support LPS activation of TLR4-HEK293 cells in an NF-kappaB-dependent manner. Parallel activation of an endothelial leukocyte adhesion molecule (ELAM)-luciferase reporter gene and IL-8 production. Mean of triplicates ± 1 SD. One representative experiment from 2 similar experiments.