Porcine skin dermatan sulfate prolongs the carotid artery occlusion time of HCII^+/+ mice. Dermatan sulfate was administered intravenously at the doses indicated. Then, 15 minutes later, vascular injury was initiated by injection of rose bengal and the time to thrombotic occlusion was determined. Error bars represent the mean ± SD. The number within each column indicates the number of mice studied. ^*P = .012 versus control (no dermatan sulfate); ^**P ≤ .001 versus control.