Figure 8.
FucTVI treatment enhances the capacity of CB-CD34+ cells to interact with BM microvessels. Purified CB-CD34+ cells were treated with FucTVI or left untreated, fluorescently labeled, and injected into NOD/SCID mice prepared for BM intravital microscopy. The numbers of cells interacting with the BM microvasculature were determined by analysis of video recordings. Shown is mean ± SEM percentage of interacting CD34+ cells from 7 independent fluorescence intravital microscopy experiments. *P = .0001; **P = .01 comparing FucTVI-treated versus untreated.