NUP98-HOXA9 accelerates BXH2 myeloid leukemia. Leukemia-free survival rates of BXH2 mice (○) and BXH2/Tg mice (•) were plotted against the age (months after birth). The NUP98-HOXA9 tg mice were backcrossed to the BXH2 strain to introduce the transgene into BXH2 genetic background, and survival rates of Tg-positive BXH2 mice were compared with those of Tg-negative littermates at the third generation.