Individual paired results of cultures with and without steroids for 13 patients with DBA grouped according to clinical status at the time of study. Results are expressed as total DAF+ cells × 105 at day 7 of liquid phase 2 per 1 × 105 total nonadherent cells plated in phase 2. Serum-free culture with IL-3/SCF with or without 1 × 10-7 M dexamethasone in both phases, plus 2 U/mL Epo in phase 2. Patient details are given in Table 1. □ indicates no dexamethasone; ▩ , added dexamethasone. Clinical response to steroids is defined as achieving transfusion independence. “Steroid dependent” indicates continuing transfusion independence on steroid therapy; “remission,” continuing transfusion independence off steroids after initial response; “refractory,” loss of steroid responsiveness after initial response, now transfusion-dependent; “not tested,” trial of steroids not yet started (UPN 13 had mild anemia not requiring treatment; UPN 20 was transfusion-dependent at time of testing).
