Figure 4.
The polymorphic marker D17mit62 is near the mouse MHC H-2 gene cluster on chromosome 17. D17Mit62 is the polymorphic marker with the highest association with anti–human factor IX antibody levels in AXB and BXA recombinant inbred mouse strains. Mouse chromosome 17 is depicted with a horizontal line. Polymorphic markers that were analyzed for their association with antibody development are shown above the line. The map positions along chromosome 17 (in centimorgans [cM] or megabases [Mb]) are shown below the line, as are genes of the histocompatibility complex H-2 locus.