Figure 5.
Expression of HLA-DR is increased in CD4+CD25+ T cells from patients with MG. (A) Representative HLA-DR expression profile for newborn, young adult, and myasthenic CD8-depleted thymocytes stained with anti-HLA-DR, anti-CD25, anti-CD4 mAbs and analyzed by flow cytometry. HLA-DR expression is shown with a solid line and the staining with an isotype IgG control with a dotted line. (B) The percentage of HLA-DR was determined among CD4+CD25- and CD4+CD25+ cells in 9 MG patient, 9 young adult and 6 newborn thymi. • represents 1 patient or 1 control. Bars indicate mean values.