Figure 6.
CD4+CD25+ thymocytes from patients with MG are enriched in Fashi cells. (A) Representative Fas expression profile for newborn, young adult normal, and myasthenic CD8-depleted thymocytes stained with anti-CD25, anti-CD95, anti-CD4 mAbs and analyzed by flow cytometry. The IgG isotype control staining is shown with a dotted line. The percentage of Fashi cells is indicated above the brackets delimiting this cell subset. (B) The percentage of Fas expression was determined among CD4+CD25- and CD4+CD25+ cells in thymi from 11 patients with MG, 9 young adults, and 10 newborns.