Figure 4.
Liver R2 images and distributions. Liver R2 images and distributions for 4 subjects with different degrees of iron overload and pathologic conditions: (A) hepatitis, (B) HH, (C) β-thalassemia, and (D) β-thalassemia/hemoglobin E. Note that the liver R2 images are superimposed on standard spin-echo images for registration purposes. Principles of construction of R2 images and distributions are described elsewhere.44 Note that to enable visualization of the heterogeneity of R2 within each liver, the color scale within each liver is adjusted for each image such that zero corresponds to voxel R2 of zero, whereas the maximum of the color scale is scaled to the maximum R2 value within the liver.