Figure 7.
Endostatin reduces mRNA expression of hPDGFB but not hTGFβ. Human PDGFB and TGFβ mRNA expression determined by real-time PCR analysis using the Light Cycler on cDNA synthesized from RNA of human CD31+ cells isolated from control- or endostatin-treated Matrigel plugs. (A) Copy numbers of human PDGFB transcripts in CD31+ cell fraction per nanogram RNA. (B) TGFβ mRNA copy numbers in CD31+ cells per nanogram RNA.