Figure 1.
Figure 1. ICAM-1 reappears on HUVEC surface after internalization of anti-ICAM nanocarriers. Kinetics of FITC-labeled anti-ICAM/NC internalization (uptake, squares) and accessibility of ICAM-1 on EC surface to 125I-labeled anti-ICAM (circles) were evaluated in cyclohexamide-treated HUVECs at 4°C (A) or at 37°C (B). Cells were activated with TNF-α in all experiments shown in the figures. Data represent M ± SEM for n = 9 wells from 3 independent experiments.

ICAM-1 reappears on HUVEC surface after internalization of anti-ICAM nanocarriers. Kinetics of FITC-labeled anti-ICAM/NC internalization (uptake, squares) and accessibility of ICAM-1 on EC surface to 125I-labeled anti-ICAM (circles) were evaluated in cyclohexamide-treated HUVECs at 4°C (A) or at 37°C (B). Cells were activated with TNF-α in all experiments shown in the figures. Data represent M ± SEM for n = 9 wells from 3 independent experiments.

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