Figure 6.
Effect of combining THC with cisplatin. The viability in the cell lines treated concurrently with IC25 concentrations of THC and cisplatin (▦) were compared with the calculated viability (□) (A). This estimated value was determined as the sum of the viabilities in cells treated with either THC or cisplatin alone. Cells were also cultured with small concentrations of THC (IC5, ⋄; and IC10, ▴) or left untreated (▪) to investigate whether these suboptimal doses could enhance the cytotoxic effects of cisplatin. Each data point represents the means and SDs of at least 4 separate experiments.