Figure 1.
The absence of donor bone marrow cell–derived IL-15 ameliorates acute GVHD mortality. Wild-type B6D2F1 mice received transplants of 5 × 106 IL-15-/- B6 splenic T cells and 1 × 107 wt B6 BM cells (▪, n = 8) or IL-15-/- B6 BM cells (□, n = 8) and were observed for acute GVHD mortality. Survival times were compared using the log-rank test: P = .005.