Figure 3.
Kaplan-Meier survival plot of MET-1 leukemia-bearing SCID/NOD mice in the small tumor burden therapeutic study. At the time of the experiment, the mice had sIL-2Rα levels of 1000 to 10 000 pg/mL. Mice in the control group received 200 μL PBS weekly for 4 weeks. Mice in the flavopiridol group received 2.5 mg/kg flavopiridol daily for 5 days. Mice in the HAT group received 100 μg HAT once per week for 4 weeks. Mice in the combination group received both flavopiridol and HAT at the same doses as those in the flavopiridol and HAT groups.