American Society of Hematology

Figure 4.

$Figure 4. Binding of scuPA and t-PA to fibrin. 125I-scuPA/suPAR (4 nM) or 125I-tPA (1.5 nM) was added to soluble fibrinogen (3 mg/mL), and thrombin (0.4 U/mL) was added for 40 minutes at 37°C. The clot was sedimented and the radioactivity in the supernatant fraction was measured and subtracted from the total. The graph shows the percentage of the total radioactivity that remained in the pellet.$

Binding of scuPA and t-PA to fibrin.¹²⁵I-scuPA/suPAR (4 nM) or ¹²⁵I-tPA (1.5 nM) was added to soluble fibrinogen (3 mg/mL), and thrombin (0.4 U/mL) was added for 40 minutes at 37°C. The clot was sedimented and the radioactivity in the supernatant fraction was measured and subtracted from the total. The graph shows the percentage of the total radioactivity that remained in the pellet.

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