Figure 10.
Effect of fibrin on plasminogen-mediated inhibition of scuPA/suPAR activity. Increasing concentrations of Glu-plasminogen were added to a solution containing 125I-fibrinogen (3 mg/mL). Clots were formed by adding thrombin as in Figure 9. scuPA/suPAR (40 nM) was added for 2 hours at 37°C and the release of radioactivity into the supernatant was measured.
