Figure 1.
The effect of APC on EPCR on monocytes and HUVECs by confocal microscopy. Monocytes and HUVECs were incubated with 100 nM APC for 2 hours and stained with EPCR antibody RCR-49, as described in “Materials and methods.” Monocytes and HUVECs are shown at × 630 magnification before treatment (A and D, respectively) and after APC incubation (B and E, respectively). Panels C and F represent further magnifications (× 4) of the boxed cells from panels B and E, respectively.