Figure 4.
Multilineage lymphoid and myeloid analysis of Smad7- and vector-transduced SRCs. FACS analysis of lymphoid and myeloid commitment markers on CD45+ human hematopoietic cells transduced with vector or Smad7 retrovirus, engrafted in the BM of a representative pair of NOD/SCID mice. (A) Analysis of myeloid markers CD33, CD13, CD14, and CD15 on CD45+ gated cells. (B) Analysis of lymphoid markers CD10 and CD19 on CD45+ gated cells.