Figure 6.
CD41– cells are of erythrocyte origin. Blood cells were analyzed by flow cytometry for their expression of CD41 (platelet) and Ter119 (erythrocyte) in uninfected mice (A, B) and in mice on day 6 of P berghei infection (C, D). The platelet set was defined by its forward scatter and side scatter (orange region in A, C) and microparticles and cell debris were excluded from the analysis (black set). The platelet subsets were color-coded in B and D based on their expression of CD41 and Ter119: the CD41+Ter119– platelet subset is purple, the CD41–Ter119+ subset is red, the CD41–Ter119– is green, and the CD41Ter199+ subset is blue. Note the colors identify the same platelet subsets in A and C. There were few orange events because virtually all cells within the platelet set were defined within the subsets.