Chronic vascular injury in eNOS. gfp chimeras induces widespread hemangioblast activity from adult HSCs. Spleen (A-B,G-H), thymus (C-D,I-J), and brain (E-F,K-L) were harvested from TRITC-perfused animals and 10-μm cryosections were prepared and mounted with Vectashield plus DAPI. iNOS.gfp (A-F) and eNOS.gfp (G-L) chimeras were examined by fluorescence microscopy. Donor gfp HSC-derived cells are green and the TRITC perfusant is red. Original magnification × 40 for panels A and G. All remaining panels are original magnification × 64.