Figure 1.
![Figure 1. Effects of perforin- or FasL-deficient CD8+ T cells on acute GVHD. Lethally irradiated bm1 mice received transplants as described in “Materials and methods” from wt B6 (wt), perforin-deficient B6 (pfp–/–), or Fas ligand–deficient B6 (gld) donors. Syngeneic B6 BM transplant recipients (syn) served as no-GVHD controls. At 30 days after BMT, liver and intestine (bottom column [•], small intestine; upper column, large intestine) were harvested and scored semiquantitatively (n = 4 mice/group). Data represent mean ± SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/105/5/10.1182_blood-2004-08-3036/6/zh80050574970001.jpeg?Expires=1735562380&Signature=FDDsx0sptRjTcp1ZY0sFQZo1lskJYz0-ClPUV5zz8lsc1wG9zLTPvBBnHlC4RkbcA3htSUnt7gC1K3viHjRbcftcJj83sYE9reGPpsrz-GKzo7wI50t6pG7dK6NxzS2PsSBMy6qnIStF9mC7BcBtMHhZbfyweugmamq2zRyhFrIxasJVHqU6u9ERTGOZGJ42d97sDbUD5Z7jF365N0TZG8d1aFGlPbv8M6i55cpIu55JXFAgDaBPhEJbZmzz6K1kyRyYgqwFTARtDR~I31fvi4ZlRkeYyDkuZmNQv~i7oI8kYWxX934-BSoIXcXtNoVbwZcUHyvcHNnI5rUTX4N2Vw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of perforin- or FasL-deficient CD8+T cells on acute GVHD. Lethally irradiated bm1 mice received transplants as described in “Materials and methods” from wt B6 (wt), perforin-deficient B6 (pfp–/–), or Fas ligand–deficient B6 (gld) donors. Syngeneic B6 BM transplant recipients (syn) served as no-GVHD controls. At 30 days after BMT, liver and intestine (bottom column [•], small intestine; upper column, large intestine) were harvested and scored semiquantitatively (n = 4 mice/group). Data represent mean ± SD.
