Figure 2.
3H3 inhibits immune complex formation and glomerulonephritis. (A) Kidneys were collected from cGVHD mice at week 12 after disease induction and were fixed in formalin. Sections from control Ig– or 3H3-treated mice were stained with H&E. (B) Kidneys from week-12 cGVHD mice were collected and snap-frozen, and sections were stained with FITC-labeled rat anti–mouse IgG. (C) 3H3 treatment completely prevented death due to cGVHD (n = 10 per group). *P < .05, between the 2 groups.