NOD HSCs engraft in B10.BR recipients in the presence of equal numbers of B10.BR HSCs. The ability of NOD HSCs to engraft in allogeneic B10.BR recipients was assessed using a modified competitive reconstitution assay.^21-23  (A) Percent engraftment of B10.BR mice given 10 000 NOD KSL cells in the presence of increasing numbers of B10.BR KSL cells. Groups shown are: no B10.BR KSL cells (n = 12); 1000 B10.BR KSL cells (n = 8); 2000 B10.BR KSL cells (n = 4); 5000 B10.BR KSL cells (n = 3); and 10 000 B10.BR KSL cells (n = 13). (B) The kinetics of allogeneic chimerism in the engrafting B10.BR mice are shown based on the number of B10.BR KSL cells coadministered with the 10 000 NOD KSL cells (▵ represents none; □, 1 × 10³; ○, 2 × 10³; ▴, 5 × 10³; and ▪, 10 × 10³).