Figure 5.
MRP8/MRP14 in Kawasaki disease. Paraffin sections of myocard biopsy specimens from patients with KD (A-C) and a control decedent (D) were stained against MRP8 (A), MRP14 (B,D), and control antibody (C). Labeled are the endothelial layer of a small vessel (small arrows), granulocytes (large black arrows) adherent to endothelial cells, and microthrombi (large white arrows). Scale bars, 20 μm (A,C-D) and 30 μm (B). (E) Serum concentrations of MRP8/MRP14 were determined in 33 healthy children and in 21 patients with KD at initial presentation, 1 day after therapy with IVIG, in the second week after treatment, and in complete clinical remission. Box plots represent median and mean values, quartiles, and the 10th and 90th percentiles (*P < .05).