Figure 3.
Survival of vaccinated mice after depletion of effector cells or blocking IFN-γ or TNF-α. C3H/Hej mice were vaccinated with 106 irradiated DA1-3b leukemic cells that had been transduced with CXCL10 (DA1-3b/CXCL10) or control empty plasmid (DA1-3b/Zeo) and injected with (A) anti-NK, (B) anti-CD4, (C) anti-CD8, (D) anti-IFN-γ, (E) anti-TNF-α, or control isotype-depleting antibodies. Mice were subsequently challenged with 105 wild-type DA1-3b cells.
