Figure 2.
![Figure 2. Evaluation of recent thymic emigrants over time. (A) Longitudinal kinetics of TREC quantification in peripheral blood mononuclear cells of treated patients (P1, P2, P4 to P9). Kinetics of P4 and P5 are shown up to the time of the clonal lymphoproliferation.24 Day 0 corresponds to the date of the treatment. (B) Phenotypic quantification of naive CD45RA (▪) and memory CD45RO (▦) CD4+ T cells at 12 months (left panel) and at last follow-up for P1 (M [months] + 47), P2 (M + 53), P4 (M + 30), P5 (M + 30), P7 (M + 24), P8 (M + 22), P9 (M + 12) (right panel). In age-matched healthy children, the mean value of naive T cells is 66% ± 10% for children younger than 1 year of age and 60% ± 5% for children 1 year and older.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/105/7/10.1182_blood-2004-07-2648/6/zh80070576190002.jpeg?Expires=1735834668&Signature=Z5xUNYO~yGD-2JrYZrEIPdZejZl7ZSSiy9eKrq9c2gq5oIfG0TpRKyfu64GYY3nWjGpD92kIJKDb-aXKHdCNJqHS-7oUFbCXMT8BfVrlaiREkKiCGZ85FXx1Suq7IFZjEvn33VXECA9UGjxgHJXT-AcN~Zccf87HtwE3ri4y3i1X54ZhTaIBpHVtqE2WNxMXvSFpKyHZx5xAv20W-vM9aHr0~QZ9c42I0ygSjQEI6dXmpg3zzylxSDxRX3-DOaZPdv7oFGjvVRCw7tS90OYl-bOPVLudUbuJGrp8RXDwN49xDbvszBB1GXJ7P894bmUnMmOfaGRsLAhglggC69IK9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Evaluation of recent thymic emigrants over time. (A) Longitudinal kinetics of TREC quantification in peripheral blood mononuclear cells of treated patients (P1, P2, P4 to P9). Kinetics of P4 and P5 are shown up to the time of the clonal lymphoproliferation.24 Day 0 corresponds to the date of the treatment. (B) Phenotypic quantification of naive CD45RA (▪) and memory CD45RO (▦) CD4+ T cells at 12 months (left panel) and at last follow-up for P1 (M [months] + 47), P2 (M + 53), P4 (M + 30), P5 (M + 30), P7 (M + 24), P8 (M + 22), P9 (M + 12) (right panel). In age-matched healthy children, the mean value of naive T cells is 66% ± 10% for children younger than 1 year of age and 60% ± 5% for children 1 year and older.
