Quantitation of IgG antibodies specific for H-Y and H-X proteins. This heatmap depicts IgG ELISA results for 39 sex-mismatched patients (A) and 29 healthy females (B) who developed antibody responses to any H-Y or H-X recombinant protein. Individual samples are represented in rows and each H-Y or H-X protein is represented in a separate column. Negative ELISA results are shown in light blue. The magnitude of positive ELISA results are represented by increasing tones of red. Below each H-Y antigen label, the mean ELISA result for the respective seropositive samples is presented.