Titration of relipidated TF in CTI-inhibited whole blood and plasma. Increasing concentrations of relipidated TF (TF/PCPS, 1:5000) were added to whole blood containing 0.1 mg/mL CTI (A) or PFP reconstituted with A23187 (a calcium ionophore)–treated platelets at 2 × 10⁸/mL (B). ▪ represents individual no. 1 (Table 1) and □ represents individual no. 6. Clotting time was determined either visually (whole blood) or using the ST4 clotting instrument (plasma).