Figure 5.
Quantitative PCR analysis of PLAG1 and PLAGL2 in a panel of 162 human AML samples.PLAGL2 (A) and PLAG1 (B) RELs. Samples are clustered in 4 cytogenetic groups: samples showing inv(16)(p13;q22), t(15;17), t(8;21), and samples without these rearrangements (other). Within each group, samples are ordered by increased PLAGL2 RELs. RELs represent the average of duplicate values and are compared with the value of 6 healthy CD34+ bone marrow samples.