Effect of FADDdn on the differentiation of ES-MDS erythroid precursors. (A) Glycophorin A (GPA) in mean percentages of positive cells (± SEM) in control and ES-MDS erythroid precursor cultures transduced by EGFP (□) or FADDdn (▦) vectors on culture days 7 and 14. (B) Diagram of terminal erythroid differentiation on day 14. Results are expressed as mean percentages of proerythroblasts (▪), basophilic erythroblasts (▦), orthochromatophilic erythroblasts (▨), and acidophilic erythroblasts (□) in 3 normal and 5 ES-MDS cultures.