Survival analysis of splenectomized and sham erythroleukemic mice. Age-matched BALB/c neonates were infected with F-MuLV according to “Materials and methods.” Splenectomy (□) and sham (▪) procedures were performed 4 weeks later followed by daily observations over the duration of the study. All deceased mice and those required to be killed according to institutional guidelines were documented according to date of death and plotted according to the method of Kaplan-Meier. Significance between splenectomy and sham groups was calculated using a Mann-Whitney U test with 2-sided P values and significant differences reflecting P < .05. Dotted horizontal line represents median survival.