Regulation of SAP expression in CD8⁺ T cells. Western blot analysis of SAP expression in CD8⁺ T cells from healthy donors (ND1, ND2, and ND3), and patients with HLH (SAP1) and XLP (SAP2 and SAP3) at a resting state and at 24 or 72 hours after activation with 10 μg/mL immobilized anti-CD3 mAbs.