BCA-1 enhances SLC-induced migration in human mature dendritic cells (DCs), B lymphocytes, and naive T lymphocytes. Chemotaxis of DCs (A), B lymphocytes (C), and T lymphocytes (E) induced by increasing concentrations of SLC in the presence (⬡) or absence (○) of 1 μM BCA-1. Chemotaxis of DCs (B), B lymphocytes (D), and T lymphocytes (F) induced by 10 nM SLC in the presence of increasing BCA-1 concentrations. For experiments with B lymphocytes, BCA-1 was applied to the upper well of the chemotaxis chamber together with the cells, and to the lower well. Mean ± SD of 3 independent experiments is shown. Percentages of maximal migration were calculated taking as 100% the number of cells migrated to 100 nM SLC for DCs, and to 1000 nM SLC for B and T lymphocytes.