Figure 2.
Effect of HLJDT, GZFLW, or HLT on proliferation of primary myeloma cells. Bone marrow mononuclear cells obtained from 5 untreated myeloma patients were cultured with 5 ng/mL of IL-6 in the presence of HLJDT (•), GZFLW (♦), or HLT (▴) at the indicated concentration for 5 days. After the culture, the cells were harvested and stained with FITC-anti-CD38, PE-anti-MPC-1, and PC5-anti-CD45 antibody and applied to a flow cytometer. Viable cell numbers in the CD38++, CD38++MPC-1-, and CD38++MPC-1+ fractions were examined and compared with those in medium alone (100%). Values shown in these figures are the mean ± 1SD of 5 cases. *P < .05.