American Society of Hematology

Figure 3.

$Figure 3. G185R NE mutant induces accelerated apoptosis of differentiating HL-60 cells. (A) Annexin V staining and flow cytometric analysis showing increased numbers of Annexin V-positive cells in G185R-transduced cells at day 7 of DMSO treatment. Percentages indicate fraction of Annexin V-positive cells. (B) Bar graph depicting the percentage of Annexin V-positive cells in transduced cells cultured in DMSO-containing media for day 0 (□), day 3 (▦), and day 7 (▪). Results shown are representative of 3 different experiments, with standard deviations.$

G185R NE mutant induces accelerated apoptosis of differentiating HL-60 cells. (A) Annexin V staining and flow cytometric analysis showing increased numbers of Annexin V-positive cells in G185R-transduced cells at day 7 of DMSO treatment. Percentages indicate fraction of Annexin V-positive cells. (B) Bar graph depicting the percentage of Annexin V-positive cells in transduced cells cultured in DMSO-containing media for day 0 (□), day 3 (▦), and day 7 (▪). Results shown are representative of 3 different experiments, with standard deviations.

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