Amelioration of perturbed lymphopoiesis in the thymus and lymph nodes of gp130^Y757F/Y757F:Stat3^+/- mice. Cellularity of (A) thymus and (C) lymph nodes from gp130^+/+ (□), gp130^Y757F/Y757F (▪), and gp130^Y757F/Y757F:Stat3^+/- (▦) mice. Data from 6 mice of each genotype are expressed as the mean ± SD. ^*P < .05 versus data from gp130^+/+ mice. (B) Thymocytes and (D) lymph node cells were subjected to dual-color flow cytometric analysis with the indicated antibodies. For dot plots, x-axis represents FITC intensity, y-axis represents PE intensity, and numbers indicate the percent of positive cells in each quadrant. For histograms, x-axis represents either FITC or PE intensity, and y-axis represents relative cell number. The numbers indicate the percent of positive cells in the marked regions. These flow cytometric profiles are representative of at least 5 mice of each genotype.