Peripheral blood indices from transgenic mice and their wild-type littermates. (A) White blood cell (WBC) counts, (B) hemoglobin (Hb) levels, (C) red blood cell (RBC) counts, and (D) platelet (PLT) counts of the transgenic mice (•) and their wild-type littermates (○) in lines 701, 705, and 706 are shown. A satistically significant difference between wild-type and transgenic mice was found only in the platelet counts; *P < .01, **P < .001. Ages of the wild-type littermates and transgenic mice ranged from 1.30 to 50.40 weeks (n = 38; mean = 13.89; SD = 8.60) and 1.30 to 60.9 weeks (n = 62; mean = 15.65; SD = 10.47), respectively. (E) Platelet counts of the transgenic mice in 3 groups containing similar age ranges are shown. The ages of groups I, II, and III ranged from 6 to 12 weeks, 12 to 24 weeks, and 24 to 92 weeks, respectively (n = 126).