Figure 2.
Lnk-deficient CFU-e progenitors are hypersensitive to Epo. Spleen cells isolated from wild-type and Lnk-deficient mice were plated in methylcellulose with varying concentrations of Epo. CFU-e numbers (mean ± standard error [SE]) were determined 2 days later. Five mice from each genotype were used. Comparing the 2 curves, at all Epo concentrations the P values are less than .05.