Effect of VEGF blockade on normal B-cell migration on and through endothelium. The experiments were performed exactly as in Figure 1. (A) Percentage of motile normal B cells on HUVECs. (B) TEM. When the donors were considered together as a group, none of the differences in motility/TEM with or without blocking anti-VEGF mAb or SU5416 were significant (P always > .4).