Figure 1.
Factor VII ratio and INR change according to VKORC1 genotype after a single oral dose of acenocoumarol. Factor VII ratio (A) corresponds to remaining factor VII, expressed as a percentage compared with baseline value, before AC intake (eg, [Factor VII 24 h after AC intake/Factor VII before AC intake] × 100). (B) INR change is expressed as the formula: (INR 24 h after AC intake – INR before AC intake/INR before AC intake) × 100. Bars represent means; factor VII ratio and INR change were significantly different between each intragroup. ***P < .01.