Figure 1.
Rejection of A20 but not of MPC11 lymphoma cells after immunization with unpulsed DCs. Mice received 2 injections of unpulsed DCs and a subsequent challenge with A20 or MPC11 cells. Mice remained tumor-free life long. For NK cell depletion, mAb TMβ1 was used. In all NK cell–depletion experiments, the same results were obtained using anti–asialo GM1 antiserum. indicates DC + A20; ⋄, A20 control; ▪,DC + MPC11;□, MPC11 control; and ×,DC + A20 + NK cell depletion.