Visual genotype graph for 16 polymorphic loci (rows) among the 246 patients (columns) with ALL treated in the Total XIIIB Protocol. Those homozygous for the major allele are depicted in blue, homozygous for the minor allele in yellow, and heterozygous are in green. For GSTM1 and GSTT1 deletions, the nonnull and the null genotypes are represented in blue and in yellow, respectively. The rare genotypes for TYMS and UGT1A1 were excluded from the plot (in white).